Overview

  • Product name
  • Description
    Rabbit polyclonal to SH3BP5
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1 and 248 of Human SH3BP5 (UniProt ID: O60239).

  • Positive control
    • THP1 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab126231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 50 kDa.

Target

  • Function
    Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
  • Tissue specificity
    Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate.
  • Sequence similarities
    Belongs to the SH3BP5 family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3BP5_HUMAN antibody
    • OTTHUMP00000208289 antibody
    • OTTHUMP00000208291 antibody
    • OTTHUMP00000208294 antibody
    • SAB antibody
    • SH3 binding protein antibody
    • SH3 domain binding protein 5 (BTK associated) antibody
    • SH3 domain binding protein 5 antibody
    • SH3 domain binding protein that preferentially associates with BTK antibody
    • SH3 domain-binding protein 5 antibody
    • SH3 domain-binding protein that preferentially associates with BTK antibody
    • SH3 domainbinding protein 5 antibody
    • SH3BP 5 antibody
    • SH3BP-5 antibody
    • Sh3bp5 antibody
    see all

Images

  • Anti-SH3BP5 antibody (ab126231) at 1/1000 dilution + THP1 whole cell lysate at 30 µg

    Predicted band size: 50 kDa



    12% SDS PAGE

References

ab126231 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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