Overview

  • Product nameAnti-SH3GL2 antibody
    See all SH3GL2 primary antibodies
  • Description
    Rabbit polyclonal to SH3GL2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 251-300 (PRREYQPKPR MSLEFPTGDS TQPNGGLSHT GTPKPSGVQM DQPCCRALYD) of Human SH3GL2 (NP_003017).

  • Positive control
    • HeLa cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab97998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionImplicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
  • Tissue specificityBrain, mostly in frontal cortex. Expressed at high level in fetal cerebellum.
  • Sequence similaritiesBelongs to the endophilin family.
    Contains 1 BAR domain.
    Contains 1 SH3 domain.
  • DomainAn N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes. The BAR domain dimer forms a rigid crescent shaped bundle of helices with the pair of second amphipathic helices protruding towards the membrane-binding surface.
  • Cellular localizationCytoplasm. Membrane. Concentrated in presynaptic nerve terminals in neurons.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA335L15.1 (SH3 domain GRB2 like 2) antibody
    • CNSA2 antibody
    • EEN B1 antibody
    • EEN-B1 antibody
    • Endophilin 1 antibody
    • Endophilin A1 antibody
    • Endophilin A1 BAR domain antibody
    • Endophilin-1 antibody
    • Endophilin-A1 antibody
    • FLJ20276 antibody
    • FLJ25015 antibody
    • OTTHUMP00000021084 antibody
    • SH3 domain containing GRB2 like protein 2 antibody
    • SH3 domain GRB2 like 2 antibody
    • SH3 domain protein 2A antibody
    • SH3 domain-containing GRB2-like protein 2 antibody
    • SH3D2A antibody
    • SH3G2_HUMAN antibody
    • Sh3gl2 antibody
    • Sh3p4 antibody
    • SH3PA antibody
    see all

Anti-SH3GL2 antibody images

  • Anti-SH3GL2 antibody (ab97998) at 1 µg/ml (in 5% skim milk / PBS buffer) + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 40 kDa

References for Anti-SH3GL2 antibody (ab97998)

ab97998 has not yet been referenced specifically in any publications.

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