Overview

  • Product nameAnti-SHC3 antibody
    See all SHC3 primary antibodies
  • Description
    Mouse polyclonal to SHC3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human protein (NP_058544.2)

  • Positive control
    • SHC3 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69355 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 64 kDa).

Target

  • FunctionSignaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • Tissue specificityMainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.
  • Sequence similaritiesContains 1 PID domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    Tyrosine phosphorylated.
  • Information by UniProt
  • Database links
  • Alternative names
    • N SHC antibody
    • N-Shc antibody
    • Neuronal Shc antibody
    • NSHC antibody
    • Protein Rai antibody
    • Rai antibody
    • SH2 domain protein C3 antibody
    • SHC (Src homology 2 domain containing) transforming protein 3 antibody
    • SHC protein C antibody
    • SHC-like protein, neuronal antibody
    • SHC-transforming protein 3 antibody
    • SHC-transforming protein C antibody
    • Shc3 antibody
    • SHC3_HUMAN antibody
    • SHCC antibody
    • Src homology 2 domain-containing transforming protein antibody
    • Src homology 2 domain-containing-transforming protein C3 antibody
    see all

Anti-SHC3 antibody images

  • All lanes : Anti-SHC3 antibody (ab69355) at 1/500 dilution

    Lane 1 : SHC3 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 64 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)

References for Anti-SHC3 antibody (ab69355)

ab69355 has not yet been referenced specifically in any publications.

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