Overview

  • Product nameAnti-SHC3 antibody
    See all SHC3 primary antibodies
  • Description
    Rabbit polyclonal to SHC3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 359-408 (RLKPRPHAPD TAQFAGKEQT YYQGRHLGDT FGEDWQQTPL RQGSSDIYST) of Human SHC3 (NP_058544).

  • Positive control
    • HepG2 cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab97972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSignaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
  • Tissue specificityMainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.
  • Sequence similaritiesContains 1 PID domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    Tyrosine phosphorylated.
  • Information by UniProt
  • Database links
  • Alternative names
    • N SHC antibody
    • N-Shc antibody
    • Neuronal Shc antibody
    • NSHC antibody
    • Protein Rai antibody
    • Rai antibody
    • SH2 domain protein C3 antibody
    • SHC (Src homology 2 domain containing) transforming protein 3 antibody
    • SHC protein C antibody
    • SHC-like protein, neuronal antibody
    • SHC-transforming protein 3 antibody
    • SHC-transforming protein C antibody
    • Shc3 antibody
    • SHC3_HUMAN antibody
    • SHCC antibody
    • Src homology 2 domain-containing transforming protein antibody
    • Src homology 2 domain-containing-transforming protein C3 antibody
    see all

Anti-SHC3 antibody images

  • Anti-SHC3 antibody (ab97972) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 64 kDa

References for Anti-SHC3 antibody (ab97972)

ab97972 has not yet been referenced specifically in any publications.

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