• Product nameAnti-SHOX antibody
    See all SHOX primary antibodies
  • Description
    Rabbit polyclonal to SHOX
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (EELTAFVSKS FDQKSKDGNG GGGGGGGKKD SITYREVLES GLARSRELGT) of human SHOX (NP_000442).

  • Positive control
    • Human fetal brain lysate.



Our Abpromise guarantee covers the use of ab84804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionControls fundamental aspects of growth and development.
  • Tissue specificitySHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
  • Involvement in diseaseDefects in SHOX are the cause of Leri-Weill dyschondrosteosis (LWD) [MIM:127300]. LWD is a dominantly inherited skeletal dysplasia characterized by moderate short stature predominantly because of short mesomelic limb segments. It is often associated with the Madelung deformity of the wrist, comprising bowing of the radius and dorsal dislocation of the distal ulna.
    Defects in SHOX are a cause of Langer mesomelic dysplasia (LMD) [MIM:249700]. LMD is an autosomal recessive rare skeletal dysplasia characterized by severe short stature owing to shortening and maldevelopment of the mesomelic and rhizomelic segments of the limbs. Associated malformations are rarely reported and intellect is normal in all affected subjects reported to date.
    Defects in SHOX are a cause of idiopathic short stature (ISS) [MIM:300582]. Idiopathic short stature is usually defined as a height below the third percentile for chronological age or minus 2 standard deviations of national height standards in the absence of specific causative disorders.
  • Sequence similaritiesBelongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • GCFX antibody
    • Growth control factor, X linked antibody
    • Homo sapiens shox gene, alternatively spliced products, complete cds antibody
    • PHOG antibody
    • Pseudoautosomal homeobox containing osteogenic antibody
    • Pseudoautosomal homeobox containing osteogenic protein antibody
    • Pseudoautosomal homeobox-containing osteogenic protein antibody
    • Short stature homeobox antibody
    • Short stature homeobox containing protein antibody
    • Short stature homeobox protein antibody
    • Short stature homeobox-containing protein antibody
    • SHOX antibody
    • SHOX_HUMAN antibody
    • SHOXY antibody
    • SS antibody
    • Turner syndrome antibody
    see all

Anti-SHOX antibody images

  • Anti-SHOX antibody (ab84804) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal brain lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 32 kDa
    Observed band size : 29 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

References for Anti-SHOX antibody (ab84804)

ab84804 has not yet been referenced specifically in any publications.

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