Overview

  • Product nameAnti-SHPRH antibody [2994C1a]
    See all SHPRH primary antibodies
  • Description
    Mouse monoclonal [2994C1a] to SHPRH
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment derived from the central region of Human SHPRH

Properties

Applications

Our Abpromise guarantee covers the use of ab84856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 193 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • FunctionE3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
  • Tissue specificityBroadly expressed.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the SNF2/RAD54 helicase family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 RING-type zinc finger.
  • DomainThe RING finger mediates E3 ubiquitin ligase activity.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA545I5.2 antibody
    • E3 ubiquitin-protein ligase SHPRH antibody
    • FLJ27258 antibody
    • FLJ37625 antibody
    • FLJ45012 antibody
    • FLJ90837 antibody
    • histone-linker antibody
    • KIAA2023 antibody
    • MGC134886 antibody
    • PHD and RING finger domain-containing helicase antibody
    • Shprh antibody
    • SHPRH_HUMAN antibody
    • SNF2 antibody
    • SNF2 histone linker PHD RING helicase antibody
    see all

Anti-SHPRH antibody [2994C1a] images

  • Anti-SHPRH antibody [2994C1a] (ab84856) + immunogen (recombinant fragment of Human SHPRH)

    Predicted band size : 193 kDa

References for Anti-SHPRH antibody [2994C1a] (ab84856)

ab84856 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"