Overview

  • Product name
  • Description
    Rabbit polyclonal to SIA8D
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within amino acids 193-222 of Human SIA8D (Q92187)

  • Positive control
    • HL-60 cell lysate, mouse spleen tissue lysate, brain tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells.
  • Tissue specificity
    Highly expressed in fetal brain, lung and kidney and in adult heart, spleen and thymus. Present to a lesser extent in adult brain, placenta, lung, large and small intestine and peripheral blood leukocytes.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 8-sialyltransferase 8D antibody
    • 8-sialyltransferase antibody
    • Alpha 2 8 sialyltransferase 8D antibody
    • Alpha-2 antibody
    • CMP N acetylneuraminate poly alpha 2 8 sialyl transferase antibody
    • CMP-N-acetylneuraminate-poly-alpha-2 antibody
    • Polysialyltransferase 1 antibody
    • Polysialyltransferase-1 antibody
    • PST antibody
    • PST1 antibody
    • SIA8D_HUMAN antibody
    • Sialyltransferase 8 alpha 2 8 polysialytransferase D antibody
    • Sialyltransferase 8D antibody
    • Sialytransferase St8Sia IV antibody
    • SIAT8-D antibody
    • SIAT8D antibody
    • ST8 alpha N acetyl neuraminide alpha 2 8 sialyltransferase 4 antibody
    • ST8Sia IV antibody
    • ST8SIA4 antibody
    • ST8SiaIV antibody
    see all

Images

  • Anti-SIA8D antibody (ab103036) at 1/100 dilution + HL60 cell lysate at 35 µg

    Predicted band size : 41 kDa
  • Anti-SIA8D antibody (ab103036) at 1/100 dilution + Mouse spleen tissue lysate at 35 µg

    Predicted band size : 41 kDa
  • Formalin fixed and paraffin embedded brain tissue labelled with ab103036 at 1/50 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

ab103036 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab103036.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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