Overview

  • Product name
  • Description
    Rabbit polyclonal to SIA8D
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-359 of Human SIA8D.

  • Positive control
    • Jurkat, Raji, THP1, NCI-H929 whole cell lysate; U373 xenograft
  • General notes
    Keep as a concentrated solution.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78% PBS, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab155497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells.
  • Tissue specificity
    Highly expressed in fetal brain, lung and kidney and in adult heart, spleen and thymus. Present to a lesser extent in adult brain, placenta, lung, large and small intestine and peripheral blood leukocytes.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 8-sialyltransferase 8D antibody
    • 8-sialyltransferase antibody
    • Alpha 2 8 sialyltransferase 8D antibody
    • Alpha-2 antibody
    • CMP N acetylneuraminate poly alpha 2 8 sialyl transferase antibody
    • CMP-N-acetylneuraminate-poly-alpha-2 antibody
    • Polysialyltransferase 1 antibody
    • Polysialyltransferase-1 antibody
    • PST antibody
    • PST1 antibody
    • SIA8D_HUMAN antibody
    • Sialyltransferase 8 alpha 2 8 polysialytransferase D antibody
    • Sialyltransferase 8D antibody
    • Sialytransferase St8Sia IV antibody
    • SIAT8-D antibody
    • SIAT8D antibody
    • ST8 alpha N acetyl neuraminide alpha 2 8 sialyltransferase 4 antibody
    • ST8Sia IV antibody
    • ST8SIA4 antibody
    • ST8SiaIV antibody
    see all

Images

  • All lanes : Anti-SIA8D antibody (ab155497) at 1/1000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Raji whole cell lysate
    Lane 3 : THP1 whole cell lysate
    Lane 4 : NCI-H929 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 41 kDa
  • Immunohistochemical analysis of paraffin-embedded U373 xenograft tissue labeling SIA8D with ab155497 at 1/500 dilution.

References

ab155497 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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