Anti-Sialyl Tn antibody [STn 219], prediluted (ab76755)

Overview

  • Product nameAnti-Sialyl Tn antibody [STn 219], prediluted
    See all Sialyl Tn primary antibodies
  • Description
    Mouse monoclonal [STn 219] to Sialyl Tn, prediluted
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Sheep, Human
  • Immunogen

    Ovine submaxillary mucin (OSM)

  • EpitopeNeuAc alpha GalNacOSer/Thr
  • Positive control
    • Human gastrointestinal tumor, prostate and ovary carcinomas.

Properties

Applications

Our Abpromise guarantee covers the use of ab76755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notesIHC-P: Ready to use.
    IHC-Fr: Ready to use.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceSialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers including breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase: ST6GalNAc I, which catalyzes the transfer of a sialic acid residue in alpha2,6-linkage to the GalNAcalpha1-O-Ser/Thr structure. The resulting disaccharide (Neu5Acalpha2-6GalNAcalpha1-O-Ser/Thr) cannot be further elongated and sialyl-Tn expression results therefore in a shortening of the O-glycan chains
    • Alternative names
      • CD175s antibody
      • Sialosyl Tn antibody
      • sTn antibody

    References for Anti-Sialyl Tn antibody [STn 219], prediluted (ab76755)

    ab76755 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"