Purified bone-marrow derived mouse IPC
Incubation of interferon producing cells with antibody 440c in vitro or administration of antibody 440c in vivo reduces secretion of IFN-alpha in response to CpG DNA without causing interferon producing cells depletion.
Our Abpromise guarantee covers the use of ab106174 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||1/50. ab18536-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.|
|Inhibition Assay||Use at an assay dependent concentration. (For inhibition of IFN-alpha secretion dilutions have to be made according to the amounts of SIGLEC H to be inactivated).|