Overview

  • Product name
    Anti-SIGLEC14 antibody [MM0550-4G4]
    See all SIGLEC14 primary antibodies
  • Description
    Mouse monoclonal [MM0550-4G4] to SIGLEC14
  • Specificity
    This antibody is known to show cross reactivity to Siglec-5
  • Tested applications
    Suitable for: WB, Neutralisingmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment of Human SIGLEC14 extracellular domain.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
  • Clonality
    Monoclonal
  • Clone number
    MM0550-4G4
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
Neutralising Use at an assay dependent dilution.

Target

  • Function
    Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.
  • Tissue specificity
    Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Also detected in lung and testis.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Sialic acid binding Ig like lectin 14 antibody
    • Sialic acid-binding Ig-like lectin 14 antibody
    • SIG14_HUMAN antibody
    • Siglec 14 antibody
    • Siglec-14 antibody
    • SIGLEC14 antibody
    see all

References

This product has been referenced in:
  • Brazil JC  et al. a3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration. J Immunol 191:4804-17 (2013). Read more (PubMed: 24068663) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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