Overview

  • Product name
  • Description
    Goat polyclonal to SIM2
  • Specificity
    This antibody is expected to recognize all reported isoforms (NP_005060.1; NP_033664.2).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Synthetic peptide:

    SDLLYTPSYS

    , corresponding to internal sequence amino acids 428-427 of Human SIM2 (NP_005060.1; NP_033664.2).

  • Positive control
    • Fetal Mouse kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab110000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 73 kDa).

Target

  • Function
    Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development.
  • Sequence similarities
    Contains 1 basic helix-loop-helix (bHLH) domain.
    Contains 1 PAC (PAS-associated C-terminal) domain.
    Contains 2 PAS (PER-ARNT-SIM) domains.
    Contains 1 Single-minded C-terminal domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • bHLHe15 antibody
    • Class E basic helix loop helix protein 15 antibody
    • Class E basic helix-loop-helix protein 15 antibody
    • MGC119447 antibody
    • SIM 2 antibody
    • SIM antibody
    • Sim2 antibody
    • SIM2_HUMAN antibody
    • Single minded homolog 2 (Drosophila) antibody
    • Single minded homolog 2 antibody
    • Single-minded homolog 2 antibody
    • Transcription factor SIM2 antibody
    see all

Images

  • Anti-SIM2 antibody (ab110000) at 0.5 µg/ml + Fetal Mouse kidney lysate at 35 µg

    Predicted band size : 73 kDa

References

ab110000 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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