Overview

  • Product nameAnti-Sin3b antibody
    See all Sin3b primary antibodies
  • Description
    Rabbit polyclonal to Sin3b
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 15-215 of Human Sin3b.

  • Positive control
    • HepG2 cell line and HCT116 whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab101843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 133 kDa.

Target

  • RelevanceActs as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • Histone deacetylase complex subunit Sin3b antibody
    • Paired amphipathic helix protein Sin3b antibody
    • SIN3 homolog B transcription regulator antibody
    • SIN3 transcription regulator family member B antibody
    • SIN3 transcription regulator homolog B antibody
    • Transcriptional corepressor Sin3b antibody
    see all

Anti-Sin3b antibody images

  • Anti-Sin3b antibody (ab101843) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 133 kDa

References for Anti-Sin3b antibody (ab101843)

ab101843 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"