Overview

  • Product nameAnti-SIPA1 antibody
    See all SIPA1 primary antibodies
  • Description
    Rabbit polyclonal to SIPA1
  • SpecificityAt least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    uman brain tissue lysate 19 amino acids from near the N-terminus of Human SIPA1 (AAH10492).

  • Positive control
    • Human brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab124202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 112 kDa.

Target

  • FunctionGTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.
  • Tissue specificityExpressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
  • Sequence similaritiesContains 1 PDZ (DHR) domain.
    Contains 1 Rap-GAP domain.
  • Cellular localizationNucleus. Cytoplasm > perinuclear region. Endomembrane system. Mostly localized in the perinuclear membraneous region.
  • Information by UniProt
  • Database links
  • Alternative names
    • GTPase activating protein Spa 1 antibody
    • GTPase-activating protein Spa-1 antibody
    • MGC102688 antibody
    • MGC17037 antibody
    • p130 SPA-1 antibody
    • p130 SPA1 antibody
    • Signal induced proliferation associated 1 antibody
    • Signal induced proliferation associated gene 1 antibody
    • Signal induced proliferation associated protein 1 antibody
    • Signal-induced proliferation-associated protein 1 antibody
    • SIPA 1 antibody
    • Sipa-1 antibody
    • Sipa1 antibody
    • SIPA1_HUMAN antibody
    • Spa1 antibody
    see all

Anti-SIPA1 antibody images

  • Anti-SIPA1 antibody (ab124202) at 1 µg/ml + Human brain tissue lysate at 15 µg

    Predicted band size : 112 kDa

References for Anti-SIPA1 antibody (ab124202)

ab124202 has not yet been referenced specifically in any publications.

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