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ab32441 has been referenced in 26 publications.

  • Chen Y  et al. Hydroquinone-induced malignant transformation of TK6 cells by facilitating SIRT1-mediated p53 degradation and up-regulating KRAS. Toxicol Lett 259:133-42 (2016). WB, IHC-P ; Human . PubMed: 27515134
  • Li C  et al. SIRT1 expression is associated with poor prognosis of lung adenocarcinoma. Onco Targets Ther 8:977-84 (2015). IHC-P ; Human . PubMed: 25995644
  • Benard A  et al. Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer. Histopathology 66:270-82 (2015). IHC-P ; Human . PubMed: 25307864
  • Mohan M  et al. Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. J Immunol 194:291-306 (2015). PubMed: 25452565
  • McGlynn LM  et al. SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients. PLoS One 10:e0131344 (2015). IHC ; Human . PubMed: 26121130
  • Antoniali G  et al. SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements. Mol Biol Cell 25:532-47 (2014). WB ; Human . PubMed: 24356447
  • Ren JH  et al. Sirtuin 1 regulates hepatitis B virus transcription and replication by targeting transcription factor AP-1. J Virol 88:2442-51 (2014). PubMed: 24335313
  • Simmons GE  et al. Frizzled 7 expression is positively regulated by SIRT1 and ß-catenin in breast cancer cells. PLoS One 9:e98861 (2014). WB ; Human . PubMed: 24897117
  • Chen X  et al. Sirt1 is a tumor promoter in lung adenocarcinoma. Oncol Lett 8:387-393 (2014). IHC-P ; Human . PubMed: 24959282
  • Derr RS  et al. High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients. BMC Cancer 14:604 (2014). IHC-P ; Human . PubMed: 25139823
  • Raynes R  et al. The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. PLoS One 8:e54364 (2013). WB ; Human . PubMed: 23349863
  • Holloway KR  et al. SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression. Mol Endocrinol 27:480-90 (2013). WB ; Human . PubMed: 23340254
  • Yu XM  et al. The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas. PLoS One 8:e66975 (2013). IHC-P . PubMed: 23805287
  • Moschen AR  et al. Adipose tissue and liver expression of SIRT1, 3, and 6 increase after extensive weight loss in morbid obesity. J Hepatol N/A:N/A (2013). PubMed: 23928404
  • Stenzinger A  et al. High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma. BMC Cancer 13:450 (2013). WB, IHC-P ; Human . PubMed: 24088390
  • Koizume S  et al. HIF2a-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res 40:5389-401 (2012). PubMed: 22402494
  • Yamagata Y  et al. Lentiviral transduction of CD34(+) cells induces genome-wide epigenetic modifications. PLoS One 7:e48943 (2012). ICC/IF ; Human . PubMed: 23145033
  • Sestito R  et al. STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation. FASEB J 25:916-27 (2011). IHC-Fr ; Human . PubMed: 21098725
  • Orecchia A  et al. Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells. PLoS One 6:e24307 (2011). IHC-P ; Human . PubMed: 21931678
  • Fiedler J  et al. MicroRNA-24 regulates vascularity after myocardial infarction. Circulation 124:720-30 (2011). WB, IHC-Fr ; Mouse . PubMed: 21788589
  • Peck B  et al. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. Mol Cancer Ther 9:844-55 (2010). WB ; Human . PubMed: 20371709
  • Levin VA  et al. Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines. J Proteome Res 9:179-91 (2010). WB ; Human . PubMed: 19894763
  • Han L  et al. SIRT1 is regulated by a PPAR{gamma}-SIRT1 negative feedback loop associated with senescence. Nucleic Acids Res 38:7458-71 (2010). WB ; Human . PubMed: 20660480
  • Jung-Hynes B  et al. Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition? J Biol Chem 284:3823-32 (2009). IP ; Human . PubMed: 19075016
  • Menghini R  et al. MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation 120:1524-32 (2009). PubMed: 19786632
  • Zhang Y  et al. Deacetylation of cortactin by SIRT1 promotes cell migration. Oncogene 28:445-60 (2009). WB, IHC-P ; Human . PubMed: 18850005