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ab62739 has been referenced in 15 publications.

  • Kim TH  et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta 1850:401-10 (2015). PubMed: 25445714
  • Kugel S  et al. Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer. Cell Rep 13:479-88 (2015). WB, ChIP ; Mouse . PubMed: 26456828
  • Silberman DM  et al. SIRT6 is required for normal retinal function. PLoS One 9:e98831 (2014). WB ; Mouse . PubMed: 24896097
  • Van Meter M  et al. SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. Nat Commun 5:5011 (2014). PubMed: 25247314
  • Simeoni F  et al. Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling. Sci Rep 3:3085 (2013). Human . PubMed: 24169447
  • Tao R  et al. Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6. J Lipid Res 54:2745-53 (2013). Mouse . PubMed: 23881913
  • Rottiers V  et al. Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR. Sci Transl Med 5:212ra162 (2013). WB . PubMed: 24259050
  • Toiber D  et al. SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling. Mol Cell 51:454-68 (2013). WB, IP ; Mouse . PubMed: 23911928
  • Mao Z  et al. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proc Natl Acad Sci U S A 109:11800-5 (2012). WB . PubMed: 22753495
  • Sebastián C  et al. The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell 151:1185-99 (2012). WB ; Mouse . PubMed: 23217706
  • Yang SJ  et al. Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats. PLoS One 6:e17057 (2011). WB ; Rat . PubMed: 21373642
  • Tao R  et al. Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene. J Biol Chem 286:14681-90 (2011). WB ; Human . PubMed: 21388966
  • Ram O  et al. Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell 147:1628-39 (2011). WB, CHIPseq ; Human . PubMed: 22196736
  • Zhong L  et al. The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1alpha. Cell 140:280-293 (2010). WB ; Mouse . PubMed: 20141841
  • Schwer B  et al. Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc Natl Acad Sci U S A : (2010). WB ; Mouse . PubMed: 21098266