Overview

  • Product nameAnti-Six3 antibody
    See all Six3 primary antibodies
  • Description
    Rabbit polyclonal to Six3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Chicken, Guinea pig, Cow, Cat, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within the C terminal amino acids 281-330 (MRSLAEPGCP THGSAESPST AASPTTSVSS LTERADTGTS ILSVTSSDSE) of Mouse Six3 (NP_035511).

  • Positive control
    • Mouse thymus lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay be involved in visual system development.
  • Involvement in diseaseDefects in SIX3 are the cause of holoprosencephaly type 2 (HPE2) [MIM:157170]. Holoprosencephaly (HPE) [MIM:236100] is the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
  • Sequence similaritiesBelongs to the SIX/Sine oculis homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Homeobox protein SIX3 antibody
    • HPE2 antibody
    • Sine oculis homeobox homolog 3 antibody
    • SIX homeobox 3 antibody
    • Six3 antibody
    • SIX3_HUMAN antibody
    see all

Anti-Six3 antibody images

  • Anti-Six3 antibody (ab105529) at 1 µg/ml + Mouse thymus lysate at 10 µg

    Predicted band size : 35 kDa

References for Anti-Six3 antibody (ab105529)

ab105529 has not yet been referenced specifically in any publications.

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