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Rabbit polyclonal to Six3
Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 137-166 of Human Six3 (NP_005404.1).
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunogen affinity purified
ab124059 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 35 kDa.
May be involved in visual system development.
Involvement in disease
Defects in SIX3 are the cause of holoprosencephaly type 2 (HPE2) [MIM:157170]. Holoprosencephaly (HPE) [MIM:236100] is the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
Belongs to the SIX/Sine oculis homeobox family.
Contains 1 homeobox DNA-binding domain.
Information by UniProt
Homeobox protein SIX3 antibody
Sine oculis homeobox homolog 3 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"