Overview

  • Product nameAnti-Six3 antibody
    See all Six3 primary antibodies
  • Description
    Rabbit polyclonal to Six3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 137-166 of Human Six3 (NP_005404.1).

  • Positive control
    • HL-60 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab124059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 35 kDa.

Target

  • FunctionMay be involved in visual system development.
  • Involvement in diseaseDefects in SIX3 are the cause of holoprosencephaly type 2 (HPE2) [MIM:157170]. Holoprosencephaly (HPE) [MIM:236100] is the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
  • Sequence similaritiesBelongs to the SIX/Sine oculis homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Homeobox protein SIX3 antibody
    • HPE2 antibody
    • Sine oculis homeobox homolog 3 antibody
    • SIX homeobox 3 antibody
    • Six3 antibody
    • SIX3_HUMAN antibody
    see all

Anti-Six3 antibody images

  • Anti-Six3 antibody (ab124059) at 1/100 dilution + HL-60 cell line lysate at 35 µg

    Predicted band size : 35 kDa

References for Anti-Six3 antibody (ab124059)

ab124059 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"