Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab58286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay be involved in visual system development.
    • Involvement in diseaseDefects in SIX3 are the cause of holoprosencephaly type 2 (HPE2) [MIM:157170]. Holoprosencephaly (HPE) [MIM:236100] is the most common structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
    • Sequence similaritiesBelongs to the SIX/Sine oculis homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Homeobox protein SIX3 antibody
      • HPE2 antibody
      • Sine oculis homeobox homolog 3 antibody
      • SIX homeobox 3 antibody
      • Six3 antibody
      • SIX3_HUMAN antibody
      see all

    Anti-Six3 antibody images



    • Predicted band size : 35 kDa
      Six3 antibody (ab58286) at 1ug/lane + 293 cell lysate at 25ug/lane.

    References for Anti-Six3 antibody (ab58286)

    ab58286 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"