Overview

  • Product nameAnti-SLAIN2 antibody
    See all SLAIN2 primary antibodies
  • Description
    Rabbit polyclonal to SLAIN2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cow
  • Immunogen

    Synthetic peptide designed within residues: SAKSGGGPGS GPRRTSSEEL RDATSLLAAG EGGLLDEVEP LRPDELERLS, corresponding to amino acids 71 - 119 of Human SLAIN2 (NP_065897).

  • Positive control
    • Fetal thymus lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG

Applications

Our Abpromise guarantee covers the use of ab94863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 63 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionBinds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase.
  • Tissue specificityWidely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain.
  • Sequence similaritiesBelongs to the SLAIN motif-containing family.
  • DomainThe N-terminus forms a two-stranded coiled coil.
  • Post-translational
    modifications
    Is highly phosphorylated during mitosis, but not during interphase. The highly phosphorylated form does not localize at microtubule plus ends and does not interact with MAPRE1 or CKAP5.
  • Cellular localizationCytoplasm > cytoskeleton. Colocalizes with microtubules. Detected at the plus end of growing microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ21611 antibody
    • KIAA1458 antibody
    • SLAI2_HUMAN antibody
    • SLAIN motif containing 2 antibody
    • SLAIN motif family member 2 antibody
    • SLAIN motif-containing protein 2 antibody
    • SLAIN2 antibody
    see all

Anti-SLAIN2 antibody images

  • Anti-SLAIN2 antibody (ab94863) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal thymus lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 63 kDa

References for Anti-SLAIN2 antibody (ab94863)

ab94863 has not yet been referenced specifically in any publications.

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