Anti-SLAM / CD150 antibody [9D1] (Allophycocyanin) (ab93526)

Overview

  • Product nameAnti-SLAM / CD150 antibody [9D1] (Allophycocyanin)
    See all SLAM / CD150 primary antibodies
  • Description
    Rat monoclonal [9D1] to SLAM / CD150 (Allophycocyanin)
  • ConjugationAllophycocyanin. Ex: 645nm, Em: 660nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    CHO cells stably transfected with Mouse SLAM/ CD150.

  • Positive control
    • Mouse thymic and splenic cell suspensions
  • General notes


    Mouse hematopoietic stem cells (HSC) can be identified using SLAM/CD150 family markers, such as CD150+CD244-CD48.

Properties

Applications

Our Abpromise guarantee covers the use of ab93526 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Use at 1 µg/test in a 100 µl volume.

Target

  • FunctionHigh-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
  • Tissue specificityConstitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation.
  • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • DomainThe most membrane-proximal SH2-binding motif interacts with SH2 domain of SH2D1A and does not need to be phosphorylated on tyrosine residues.
  • Post-translational
    modifications
    Phosphorylated by FYN.
  • Cellular localizationCell membrane. Present on the surface of B-cells and T-cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4933415F16 antibody
    • AA177906 antibody
    • CD 150 antibody
    • CD150 antibody
    • CD150 antigen antibody
    • CDw150 antibody
    • Estm51 antibody
    • Ipo 3 antibody
    • IPO-3 antibody
    • Ipo3 antibody
    • MGC151472 antibody
    • MGC151476 antibody
    • OTTHUMP00000025670 antibody
    • OTTHUMP00000060252 antibody
    • RGD1560634 antibody
    • Signaling lymphocytic activation molecule antibody
    • Signaling lymphocytic activation molecule family member 1 antibody
    • Signaling lymphocytic activation molecule family member 1, isoform CRA_a antibody
    • Signaling lymphocytic activation molecule family member 1, isoform CRA_b antibody
    • Signaling lymphocytic activation molecule precursor antibody
    • Slaf1 antibody
    • SLAF1_HUMAN antibody
    • SLAM family, member 1 antibody
    • Slamf 1 antibody
    • SLAMF1 antibody
    • SLAMF1 protein antibody
    see all

Anti-SLAM / CD150 antibody [9D1] (Allophycocyanin) images

  • ab93526, at 0.5 µg, staining SLAM/CD150 in C57Bl/6 splenocytes by Flow Cytometry. Total viable cells were used for analysis, and appropriate isotype controls were tested.

References for Anti-SLAM / CD150 antibody [9D1] (Allophycocyanin) (ab93526)

ab93526 has not yet been referenced specifically in any publications.

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