Anti-SLAM / CD150 antibody [9D1] (Phycoerythrin) (ab33708)

Overview

  • Product nameAnti-SLAM / CD150 antibody [9D1] (Phycoerythrin)
    See all SLAM / CD150 primary antibodies
  • Description
    Rat monoclonal [9D1] to SLAM / CD150 (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applicationsSuitable for: Functional Studies, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    CHO cells stably transfected with mouse CD150.

Properties

Applications

Our Abpromise guarantee covers the use of ab33708 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies
Flow Cyt
  • Application notesFlow Cyt: Use 10µl to label 106 cells in 100 µl.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionHigh-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
    • Tissue specificityConstitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation.
    • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • DomainThe most membrane-proximal SH2-binding motif interacts with SH2 domain of SH2D1A and does not need to be phosphorylated on tyrosine residues.
    • Post-translational
      modifications
      Phosphorylated by FYN.
    • Cellular localizationCell membrane. Present on the surface of B-cells and T-cells.
    • Information by UniProt
    • Database links
    • Alternative names
      • 4933415F16 antibody
      • AA177906 antibody
      • CD 150 antibody
      • CD150 antibody
      • CD150 antigen antibody
      • CDw150 antibody
      • Estm51 antibody
      • Ipo 3 antibody
      • IPO-3 antibody
      • Ipo3 antibody
      • MGC151472 antibody
      • MGC151476 antibody
      • OTTHUMP00000025670 antibody
      • OTTHUMP00000060252 antibody
      • RGD1560634 antibody
      • Signaling lymphocytic activation molecule antibody
      • Signaling lymphocytic activation molecule family member 1 antibody
      • Signaling lymphocytic activation molecule family member 1, isoform CRA_a antibody
      • Signaling lymphocytic activation molecule family member 1, isoform CRA_b antibody
      • Signaling lymphocytic activation molecule precursor antibody
      • Slaf1 antibody
      • SLAF1_HUMAN antibody
      • SLAM family, member 1 antibody
      • Slamf 1 antibody
      • SLAMF1 antibody
      • SLAMF1 protein antibody
      see all

    References for Anti-SLAM / CD150 antibody [9D1] (Phycoerythrin) (ab33708)

    ab33708 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"