Overview

  • Product name
    Anti-SLC16A12 antibody
  • Description
    Rabbit polyclonal to SLC16A12
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 49-98 (WMIVAGCFLV TICTRAVTRC ISIFFVEFQT YFTQDYAQTA WIHSIVDCVT) of Human SLC16A12 (NP_998771).

  • Positive control
    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.
  • Tissue specificity
    Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens.
  • Involvement in disease
    Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.
  • Sequence similarities
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CJMG antibody
    • DKFZp686E188 antibody
    • MCT 12 antibody
    • MCT12 antibody
    • Monocarboxylate transporter 12 antibody
    • MOT12_HUMAN antibody
    • OTTHUMP00000020064 antibody
    • Slc16a12 antibody
    • Solute carrier family 16 member 12 antibody
    • Solute carrier family 16, member 12 (monocarboxylic acid transporter 12) antibody
    see all

Images

  • All lanes : Anti-SLC16A12 antibody (ab105834) at 0.5 µg/ml

    Lane 1 : MW marker
    Lane 2 : Jurkat cell lysate at 10 µg


    Predicted band size : 53 kDa

References

ab105834 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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