Anti-SLC20A2/PIT2 antibody (ab191182)
Key features and details
- Rabbit polyclonal to SLC20A2/PIT2
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-SLC20A2/PIT2 antibody
See all SLC20A2/PIT2 primary antibodies -
Description
Rabbit polyclonal to SLC20A2/PIT2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide within Human SLC20A2/PIT2 aa 300-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q08357 -
Positive control
- Whole cell lysate from HeLa, 293T, Jurkat, mouse TCMK-1 and mouse NIH3T3 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7-8 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191182 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/2000 - 1/10000. Predicted molecular weight: 70 kDa.
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Notes |
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WB
1/2000 - 1/10000. Predicted molecular weight: 70 kDa. |
Target
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Function
Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants. -
Tissue specificity
Ubiquitously expressed. -
Sequence similarities
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 6575 Human
- Entrez Gene: 20516 Mouse
- Omim: 158378 Human
- SwissProt: Q08357 Human
- SwissProt: Q80UP8 Mouse
- Unigene: 653173 Human
- Unigene: 323901 Mouse
- Unigene: 378231 Mouse
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Alternative names
- Gibbon ape leukemia virus receptor 2 antibody
- Gibbon leukemia virus receptor 2 antibody
- GLVR 2 antibody
see all
Images
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All lanes : Anti-SLC20A2/PIT2 antibody (ab191182) at 0.1 µg/ml
Lane 1 : Whole cell lysate from HeLa cells
Lane 2 : Whole cell lysate from 293T cells
Lane 3 : Whole cell lysate from Jurkat cells
Lane 4 : Whole cell lysate from TCMK-1 cells
Lane 5 : Whole cell lysate from NIH3T3 cells
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 70 kDa
Exposure time: 3 minutes
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab191182 has been referenced in 1 publication.
- Huang Y et al. IRF1-mediated downregulation of PGC1a contributes to cardiorenal syndrome type 4. Nat Commun 11:4664 (2020). PubMed: 32938919