Overview

  • Product nameAnti-SLC22A11 antibody
  • Description
    Rabbit polyclonal to SLC22A11
  • Tested applicationsSuitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to a region of Human SLC22A11

  • Positive control
    • Human Fetal liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab76385 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/312500.

ICC/IF Use at an assay dependent concentration. PubMed: 23516613

Target

  • RelevanceSLC22A11 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. It is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. SLC22A11 mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.
  • Cellular localizationCell membrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • hOAT4 antibody
    • MGC34282 antibody
    • OAT4 antibody
    • Organic anion transporter 4 antibody
    • Solute carrier family 22 (organic anion/urate transporter) member 11 antibody
    • Solute carrier family 22 member 11 antibody
    see all

Anti-SLC22A11 antibody images

  • Anti-SLC22A11 antibody (ab76385) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 60 kDa
    Observed band size : 60 kDa

References for Anti-SLC22A11 antibody (ab76385)

This product has been referenced in:
  • DesRochers TM  et al. Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity. PLoS One 8:e59219 (2013). IHC-P, ICC/IF ; Human . Read more (PubMed: 23516613) »
  • Woo CS  et al. Fate of the teratogenic and carcinogenic ochratoxin A in human perfused placenta. Toxicol Lett 208:92-9 (2012). WB ; Human . Read more (PubMed: 22037670) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab76385.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"