Anti-SLC22A7/OAT2 antibody - C-terminal (ab191018)
Key features and details
- Rabbit polyclonal to SLC22A7/OAT2 - C-terminal
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-SLC22A7/OAT2 antibody - C-terminal -
Description
Rabbit polyclonal to SLC22A7/OAT2 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human SLC22A7/OAT2 aa 500 to the C-terminus (C terminal).
Database link: Q9Y694 -
Positive control
- Rat liver tissue lysate. Human placenta tissue, 293T and SMMC cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191018 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
Use a concentration of 0.1 - 0.5 µg/ml.
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Notes |
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WB
Use a concentration of 0.1 - 0.5 µg/ml. |
Target
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Function
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate. -
Tissue specificity
Expressed in liver and kidney. -
Sequence similarities
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. -
Cellular localization
Basolateral cell membrane. Apical side of the renal tubule. - Information by UniProt
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Database links
- Entrez Gene: 10864 Human
- Entrez Gene: 108114 Mouse
- Entrez Gene: 89776 Rat
- Omim: 604995 Human
- SwissProt: Q9Y694 Human
- SwissProt: Q91WU2 Mouse
- SwissProt: Q5RLM2 Rat
- SwissProt: Q63314 Rat
see all -
Alternative names
- hOAT2 antibody
- liver specific transporter antibody
- NLT antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab191018 has been referenced in 1 publication.
- Xu C et al. The altered renal and hepatic expression of solute carrier transporters (SLCs) in type 1 diabetic mice. PLoS One 10:e0120760 (2015). PubMed: 25789863