Overview

  • Product nameAnti-SLC22A8 antibody
    See all SLC22A8 primary antibodies
  • Description
    Mouse polyclonal to SLC22A8
  • SpecificityThis antibody is reactive against mammalian transfected lysate.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    SLC22A8 (NP_004245, 1 a.a. ~ 542 a.a) human protein.

  • Positive control
    • Transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 60 kDa).

Target

  • FunctionPlays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
  • Tissue specificityExpressed in kidney.
  • Sequence similaritiesBelongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
  • Cellular localizationBasolateral cell membrane. Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity).
  • Information by UniProt
  • Database links
  • Alternative names
    • hOAT3 antibody
    • OAT3 antibody
    • Organic anion transporter 3 antibody
    • S22A8_HUMAN antibody
    • SLC22A8 antibody
    • Solute carrier family 22 (organic anion transporter), member 8 antibody
    • Solute carrier family 22 member 8 antibody
    see all

Anti-SLC22A8 antibody images

  • All lanes : Anti-SLC22A8 antibody (ab69883) at 1/500 dilution

    Lane 1 : SLC22A8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 60 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

References for Anti-SLC22A8 antibody (ab69883)

This product has been referenced in:
  • Kunin M  et al. Urinary organic anion transporter protein profiles in AKI. Nephrol Dial Transplant 27:1387-95 (2012). WB ; Human . Read more (PubMed: 21945944) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"