Overview

  • Product name
    Anti-SLC24A5 antibody
  • Description
    Goat polyclonal to SLC24A5
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Dog, Human
  • Immunogen

    Synthetic peptide:

    TTPDCRKKFWKN

    , corresponding to internal sequence amino acids 321-332 of Human SLC24A5

  • Positive control
    • Human Skin lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab50421 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: 1/2000.
    WB: Use at a concentration of 2 µg/ml. Detects a band of approximately 40 kDa in mouse (predicted molecular weight: 55 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
    • Sequence similarities
      Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
    • Cellular localization
      Membrane. Melanosome. Enriched in late-stage melanosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • Ion transporter JSX antibody
      • JSX antibody
      • Na(+)/K(+)/Ca(2+)-exchange protein 5 antibody
      • NCKX5 antibody
      • NCKX5_HUMAN antibody
      • Slc24a5 antibody
      • Sodium/potassium/calcium exchanger 5 antibody
      • Solute carrier family 24 (sodium/potassium/calcium exchanger),member 5 antibody
      • Solute carrier family 24 member 5 antibody
      • Solute carrier family 24,member 5 antibody
      see all

    Images

    References

    This product has been referenced in:
    • Shumilina E  et al. Regulation of calcium signaling in dendritic cells by 1,25-dihydroxyvitamin D3. FASEB J 24:1989-96 (2010). WB ; Mouse . Read more (PubMed: 20124438) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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