Overview

  • Product nameAnti-SLC25A12 antibody
    See all SLC25A12 primary antibodies
  • Description
    Rabbit polyclonal to SLC25A12
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence of the Human SLC25A12 protein (O75746).

  • Positive control
    • Human prostate carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab111415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionCalcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle.
  • Tissue specificityHigh levels in heart and skeletal muscle, low in brain and very low in kidney.
  • Involvement in diseaseDefects in SLC25A12 are the cause of aspartate-glutamate carrier 1 deficiency (AGC1D) [MIM:612949]; also called global cerebral hypomyelination. This syndrome consists of a child severe psychomotor retardation, hypotonia and hypomyelination of the central nervous system.
  • Sequence similaritiesBelongs to the mitochondrial carrier family.
    Contains 4 EF-hand domains.
    Contains 3 Solcar repeats.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGC1 antibody
    • Araceli hiperlarga antibody
    • ARALAR antibody
    • ARALAR1 antibody
    • Calcium binding mitochondrial carrier superfamily member antibody
    • Calcium binding mitochondrial carrier superfamily member Aralar1 antibody
    • Calcium-binding mitochondrial carrier protein Aralar1 antibody
    • CMC1_HUMAN antibody
    • Mitochondrial aspartate glutamate carrier 1 antibody
    • SLC25A12 antibody
    • Solute carrier family 25 (aspartate/glutamate carrier) member 12 antibody
    • Solute carrier family 25 (mitochondrial carrier Aralar) member 12 antibody
    • Solute carrier family 25 member 12 antibody
    • solute carrier family 25, member 12 antibody
    see all

Anti-SLC25A12 antibody images

  • Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using SLC25A12 Antibody (ab111415). The picture on the right is treated with the synthesized peptide.

References for Anti-SLC25A12 antibody (ab111415)

ab111415 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111415.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"