• Product nameAnti-SLC25A13 antibody
    See all SLC25A13 primary antibodies
  • Description
    Mouse polyclonal to SLC25A13
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human SLC25A13 (NP_055066.1, amino acids 1-675).

  • Positive control
    • Human liver lysate, SLC25A13 transfected 293T cell lysate.


Our Abpromise guarantee covers the use of ab89098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 74 kDa.


  • FunctionCatalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.
  • Tissue specificityHigh levels in liver and low levels in kidney, pancreas, placenta, heart and brain.
  • Involvement in diseaseDefects in SLC25A13 are the cause of citrullinemia type 2 (CTLN2) [MIM:603471]. Citrullinemia belongs to the urea cycle disorders. It is an autosomal recessive disease characterized primarily by elevated serum and urine citrulline levels. Ammonia intoxication is another manifestation. CTLN2 is characterized by neuropsychiatric symptoms including abnormal behaviors, loss of memory, seizures and coma. Death can result from brain edema. Onset is sudden and usually between the ages of 20 and 50 years.
    Defects in SLC25A13 are the cause of neonatal intrahepatic cholestasis due to citrin deficiency (NICCD) [MIM:605814]. NICCD is a form of citrullinemia type 2 with neonatal onset. NICCD is characterized by suppression of the bile flow, hepatic fibrosis, low birth weight, growth retardation, hypoproteinemia, variable liver dysfunction. NICCD is generally not severe and symptoms disappear by one year of age with an appropriate diet. Years or even decades later, however, some individuals develop the characteristic features of citrullinemia type 2 with neuropsychiatric symptoms.
  • Sequence similaritiesBelongs to the mitochondrial carrier family.
    Contains 4 EF-hand domains.
    Contains 3 Solcar repeats.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI785475 antibody
    • ARALAR2 antibody
    • Calcium binding mitochondrial carrier protein Aralar2 antibody
    • Calcium-binding mitochondrial carrier protein Aralar2 antibody
    • Citrin antibody
    • CMC2_HUMAN antibody
    • CTLN2 antibody
    • Ctrn antibody
    • Mitochondrial aspartate glutamate carrier 2 antibody
    • RGD1565889 antibody
    • Slc25a13 antibody
    • Solute carrier family 25 (citrin) member 13 antibody
    • Solute carrier family 25 member 13 (citrin) antibody
    • Solute carrier family 25 member 13 antibody
    see all

Anti-SLC25A13 antibody images

  • Anti-SLC25A13 antibody (ab89098) at 1/500 dilution + Human liver lysate at 50 µg

    Predicted band size : 74 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SLC25A13 antibody (ab89098) at 1/500 dilution

    Lane 1 : SLC25A13 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 74 kDa
    Observed band size : 74 kDa

References for Anti-SLC25A13 antibody (ab89098)

ab89098 has not yet been referenced specifically in any publications.

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