Overview

  • Product nameAnti-SLC25A3 antibody
    See all SLC25A3 primary antibodies
  • Description
    Mouse polyclonal to SLC25A3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length SLC25A3 protein (Human)

  • Positive control
    • 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Detects bands of approximately 34 and 40 kDa (predicted molecular weight: 40 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionTransport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
    • Involvement in diseaseDefects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773]. MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life.
    • Sequence similaritiesBelongs to the mitochondrial carrier family.
      Contains 3 Solcar repeats.
    • Cellular localizationMitochondrion inner membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • mitochondrial antibody
      • Mitochondrial phosphate carrier protein antibody
      • MPCP_HUMAN antibody
      • OK/SW cl.48 antibody
      • PHC antibody
      • Phosphate carrier protein antibody
      • Phosphate carrier protein mitochondrial antibody
      • Phosphate carrier protein mitochondrial precursor antibody
      • Phosphate transport protein antibody
      • PTP antibody
      • Slc25a3 antibody
      • Solute carrier family 25 member 3 antibody
      • Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
      see all

    Anti-SLC25A3 antibody images

    • All lanes : Anti-SLC25A3 antibody (ab67121) at 1/500 dilution

      Lane 1 : SLC25A3 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg/ml per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 40 kDa
      Observed band size : 40 kDa
      Additional bands at : 34 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-SLC25A3 antibody (ab67121)

    ab67121 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Sample Rat Tissue lysate - other (brain cortex mitochondria)
    Loading amount 50 µg
    Specification brain cortex mitochondria
    Gel Running Conditions Reduced Denaturing (SDS-PAGE 12%)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
    Username

    Abcam user community

    Verified customer

    Submitted Oct 22 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"