Overview

  • Product nameAnti-SLC25A3 antibody
    See all SLC25A3 primary antibodies
  • Description
    Mouse polyclonal to SLC25A3
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human SLC25A3 protein (NP_002626.1)

  • Positive control
    • Human pancreas tissue lysate, SLC25A3 transfected 293T cell line lysate and HeLa cells.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab89117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • FunctionTransport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
  • Involvement in diseaseDefects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773]. MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life.
  • Sequence similaritiesBelongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • mitochondrial antibody
    • Mitochondrial phosphate carrier protein antibody
    • MPCP_HUMAN antibody
    • OK/SW cl.48 antibody
    • PHC antibody
    • Phosphate carrier protein antibody
    • Phosphate carrier protein mitochondrial antibody
    • Phosphate carrier protein mitochondrial precursor antibody
    • Phosphate transport protein antibody
    • PTP antibody
    • Slc25a3 antibody
    • Solute carrier family 25 member 3 antibody
    • Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
    see all

Anti-SLC25A3 antibody images

  • Anti-SLC25A3 antibody (ab89117) at 1 µg/ml + Human pancreas tissue lysate at 50 µg

    Predicted band size : 40 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SLC25A3 antibody (ab89117) at 1 µg/ml

    Lane 1 : SLC25A3 transfected 293T cell line lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.
  • ab89117, at 10 µg/ml staining SLC25A3 in HeLa cells by Immunofluorescence.

References for Anti-SLC25A3 antibody (ab89117)

ab89117 has not yet been referenced specifically in any publications.

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