Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC25A6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-298 of Human SLC25A6 (UniProt ID: P12236).

  • Positive control
    • 293T whole cell lysate, HeLa cells, Cal27 xenograft

Properties

Applications

Our Abpromise guarantee covers the use of ab154007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
  • Sequence similarities
    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • Cellular localization
    Mitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAC3 antibody
    • Adenine nucleotide translocator 3 antibody
    • ADP antibody
    • ADP ATP carrier protein 3 antibody
    • ADP ATP carrier protein isoform T2 antibody
    • ADP ATP carrier protein liver antibody
    • ADP/ATP translocase 3 antibody
    • ADP/ATP translocator of liver antibody
    • ADT3_HUMAN antibody
    • ANT 2 antibody
    • ANT 3 antibody
    • ANT antibody
    • ANT3 antibody
    • ANT3Y antibody
    • ATP carrier protein 3 antibody
    • ATP carrier protein antibody
    • CDABP0051 antibody
    • isoform T2 antibody
    • MGC17525 antibody
    • SLC25A6 antibody
    • Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6 antibody
    • Solute carrier family 25 member 6 antibody
    see all

Images

  • Anti-SLC25A6 antibody (ab154007) at 1/2000 dilution + 293T whole cell
    lysate at 30 µg

    Predicted band size: 33 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Cal27 xenograft labeling SLC25A6 with ab154007 antibody at 1/500.
  • Immunofluorescent analysis of methanol-fixed HeLa cells labeling SLC25A6 with ab154007 at 1/500 dilution. Lower panel costained with Hoechst 33342.

References

This product has been referenced in:
  • Kang Y  et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. Elife 5:N/A (2016). Read more (PubMed: 27554484) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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