Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC25A6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human SLC25A6 aa 121-170. The exact sequence is proprietary. (NP_001627.2).
    Sequence:

    GAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGI


    Database link: P12236

  • Positive control
    • Human brain, cerebellum tissue; HepG2 and 293 cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab189280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 33 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function
    Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
  • Sequence similarities
    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • Cellular localization
    Mitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAC3 antibody
    • Adenine nucleotide translocator 3 antibody
    • ADP antibody
    • ADP ATP carrier protein 3 antibody
    • ADP ATP carrier protein isoform T2 antibody
    • ADP ATP carrier protein liver antibody
    • ADP/ATP translocase 3 antibody
    • ADP/ATP translocator of liver antibody
    • ADT3_HUMAN antibody
    • ANT 2 antibody
    • ANT 3 antibody
    • ANT antibody
    • ANT3 antibody
    • ANT3Y antibody
    • ATP carrier protein 3 antibody
    • ATP carrier protein antibody
    • CDABP0051 antibody
    • isoform T2 antibody
    • MGC17525 antibody
    • SLC25A6 antibody
    • Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6 antibody
    • Solute carrier family 25 member 6 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain cerebellum tissue labeling SLC25A6 with ab189280 at 5 µg/ml.

  • All lanes : Anti-SLC25A6 antibody (ab189280) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : 293 cell extract
    Lane 3 : HepG2 cell extract with immunizing peptide

    Predicted band size: 33 kDa

References

ab189280 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab189280.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up