The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
FunctionCatalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Sequence similaritiesBelongs to the mitochondrial carrier family. Contains 3 Solcar repeats.
Cellular localizationMitochondrion inner membrane. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.