Overview

  • Product nameAnti-SLC30A5 antibody
  • Description
    Mouse monoclonal to SLC30A5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-119 of Human SLC30A5

Properties

Applications

Our Abpromise guarantee covers the use of ab57590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionFunctions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP.
    • Tissue specificityUbiquitously expressed. Highly expressed in pancreas, liver and kidney. Expressed abundantly in insulin-containing beta cells, undetectable in other endocrine cell types including glucagon-secreting alpha cells and most acinar cells.
    • Sequence similaritiesBelongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
    • Cellular localizationGolgi apparatus > trans-Golgi network membrane. Perimeter of granules, localizes to the brush border membrane of the enterocyte. Concentrated in early compartments of the secretory pathway such as COPII-coated vesicles.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZp686F23142 antibody
      • FLJ12496 antibody
      • FLJ12756 antibody
      • hZTL1 antibody
      • MGC5499 antibody
      • Putative uncharacterized protein DKFZp686F23142 antibody
      • Slc30a5 antibody
      • Solute carrier family 30 (zinc transporter) member 5 antibody
      • Solute carrier family 30 (Zinc transporter), member 5 isoform CRA a antibody
      • Solute carrier family 30 member 5 antibody
      • Zinc transporter 5 antibody
      • Zinc transporter ZnT 5 antibody
      • Zinc transporter ZTL1 antibody
      • ZNT 5 antibody
      • ZnT-5 antibody
      • ZnT-like transporter 1 antibody
      • ZNT5 antibody
      • ZNT5_HUMAN antibody
      • ZNTL 1 antibody
      • ZNTL1 antibody
      • ZTL 1 antibody
      • ZTL1 antibody
      see all

    Anti-SLC30A5 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57590 SLC30A5 antibody at 1ug/ml. Predicted band size of immunogen is 39 kDa

    References for Anti-SLC30A5 antibody (ab57590)

    ab57590 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57590.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"