Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC35D1
  • Specificity
    ab106523 is predicted not to cross-react with the highly homologous SLC35D2.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 14 amino acid synthetic peptide near the N terminus of Human SLC35D1 (NP_055954).

  • Positive control
    • A20 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab106523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 39 kDa.

Target

  • Function
    Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
  • Tissue specificity
    Ubiquitous.
  • Involvement in disease
    Defects in SLC35D1 are a cause of Schneckenbecken dysplasia (SCHBCKD) [MIM:269250]. Schneckenbecken dysplagia is a rare, autosomal recessive, lethal short-limbed skeletal dysplasia with platyspondylia.
  • Sequence similarities
    Belongs to the TPT transporter family. SLC35D subfamily.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0260 antibody
    • MGC138236 antibody
    • S35D1_HUMAN antibody
    • SLC35D1 antibody
    • Solute carrier family 35 (UDP GlcA/UDP GalNAc transporter), member D1 antibody
    • Solute carrier family 35 (UDP glucuronic acid/UDP N acetylgalactosamine dual transporter), member D1 antibody
    • Solute carrier family 35 member D1 antibody
    • UDP galactose transporter related 7 antibody
    • UDP-galactose transporter-related protein 7 antibody
    • UDP-GlcA/UDP-GalNAc transporter antibody
    • UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter antibody
    • UGTrel7 antibody
    see all

Images

  • Lane 1 : Anti-SLC35D1 antibody (ab106523) at 1 µg/ml
    Lane 2 : Anti-SLC35D1 antibody (ab106523) at 2 µg/ml

    Lane 1 : A20 cell lysate
    Lane 2 : A20 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 39 kDa

References

ab106523 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab106523.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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