SpecificityAt least two isoforms of SLC39A2 are known to exist; ab118619 antibody will
recognize only the shorter isoform. ab118619 antibody reacts with Human, Mouse and Rat and is predicted to not cross-react with other ZIP family members or with other Human proteins based on sequence homology.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use at an assay dependent concentration.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa.
FunctionMediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.
Tissue specificityExpressed only in prostate and uterine epithelial cells.
Sequence similaritiesBelongs to the ZIP transporter (TC 2.A.5) family.