Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC39A4
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Cow
  • Immunogen

    Synthetic peptide corresponding to Human SLC39A4 aa 22-51 (N terminal).
    Sequence:

    ASPPAGLLS LLTSGQGALD QEALGGLLNTL

  • Positive control
    • Transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 68 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.
  • Tissue specificity
    Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.
  • Involvement in disease
    Acrodermatitis enteropathica, zinc-deficiency type
  • Sequence similarities
    Belongs to the ZIP transporter (TC 2.A.5) family.
  • Cellular localization
    Cell membrane. Recycling endosome membrane. Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1600025H15Rik antibody
    • Acrodermatitis enteropathica zinc deficiency type antibody
    • Activated in W/Wv mouse stomach 2 antibody
    • AEZ antibody
    • AU041686 antibody
    • AWMS2 antibody
    • FLJ20327 antibody
    • MGC156705 antibody
    • MGC74741 antibody
    • S39A4_HUMAN antibody
    • Slc39a4 antibody
    • Solute carrier family 39 member 4 antibody
    • Ssolute carrier family 39 zinc transporter member 4 antibody
    • Zinc transporter ZIP4 antibody
    • ZIP-4 antibody
    • ZIP4 antibody
    • Zrt and Irt like protein 4 antibody
    • Zrt- and Irt-like protein 4 antibody
    see all

Images

  • Anti-SLC39A4 antibody (ab80494) at 1 µg/ml + SLC39A4-transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 - 1/100000

    Predicted band size: 68 kDa
    Observed band size: 64 kDa (why is the actual band size different from the predicted?)

References

ab80494 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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