Overview

  • Product nameAnti-SLC4A8 antibody
    See all SLC4A8 primary antibodies
  • Description
    Rabbit polyclonal to SLC4A8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-255 of the Human SLC4A8 protein (Q2Y0W8).

  • Positive control
    • IMR32 and U87-MG whole cell lysates.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.58% Tris, 20% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab125910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 117 kDa.

Target

  • FunctionMediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
  • Tissue specificityExpressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed in pancreas and kidney cortex.
  • Sequence similaritiesBelongs to the anion exchanger (TC 2.A.31) family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody
    • Electroneutral sodium bicarbonate exchanger 1 antibody
    • k-NBC3 antibody
    • S4A8_HUMAN antibody
    • Slc4a8 antibody
    • SLC4A8 protein antibody
    • Solute carrier family 4 member 8 antibody
    see all

Anti-SLC4A8 antibody images

  • Anti-SLC4A8 antibody (ab125910) at 1/1000 dilution + Human U87-M6 whole cell lysate at 30 µg

    Predicted band size : 117 kDa

References for Anti-SLC4A8 antibody (ab125910)

ab125910 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125910.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"