Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC5A11
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the extracellular domain of SLC5A11 (Human) conjugated to KLH

  • Positive control
    • Human brain cortex

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.7
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab61018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
  • Tissue specificity
    Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.
  • Sequence similarities
    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Form
    There are 4 isoforms produced by alternative splicing.
  • Alternative names
    • homolog of rabbit KST1 antibody
    • KST1 antibody
    • Na(+)/myo-inositol cotransporter 2 antibody
    • na+/myo-inositol cotransporter 2 antibody
    • putative sodium-coupled cotransporter RKST1 antibody
    • RKST1 antibody
    • SC5AB_HUMAN antibody
    • SGLT6 antibody
    • SLC5A11 antibody
    • SMIT2 antibody
    • Sodium-dependent glucose cotransporter antibody
    • Sodium/glucose cotransporter KST1 antibody
    • Sodium/myo-inositol cotransporter 2 antibody
    • Sodium/myo-inositol transporter 2 antibody
    • solute carrier family 5 (sodium/glucose cotransporter), member 11 antibody
    • Solute carrier family 5 member 11 antibody
    see all

Images

  • ab61018 at 10µg/ml staining formalin fixed paraffin embedded brain cortex tissue

References

ab61018 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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