Overview

  • Product name
    Anti-SLC5A12 antibody
  • Description
    Rabbit polyclonal to SLC5A12
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, between amino acids 583-613 from the C-terminal region of Human SLC5A12 (NP_848593.2).

  • Positive control
    • CEM cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab107749 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 68 kDa.

Target

  • Function
    Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.
  • Sequence similarities
    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Cellular localization
    Apical cell membrane. Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI315119 antibody
    • D630015G19 antibody
    • DKFZp564G223 antibody
    • Electroneutral sodium monocarboxylate cotransporter antibody
    • Low-affinity sodium-lactate cotransporter antibody
    • MGC52019 antibody
    • RGD1311652 antibody
    • RP24-331J23.1 antibody
    • SC5AC_HUMAN antibody
    • Slc5a12 antibody
    • SMCT2 antibody
    • Sodium-coupled monocarboxylate transporter 2 antibody
    • Solute carrier family 5 member 12 antibody
    see all

Images

  • Anti-SLC5A12 antibody (ab107749) at 1/100 dilution + CEM cell line lysate at 35 µg

    Predicted band size : 68 kDa

References

ab107749 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab107749.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up