Overview

  • Product nameAnti-SLC6A8 antibody
    See all SLC6A8 primary antibodies
  • Description
    Rabbit polyclonal to SLC6A8
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    A region within synthetic peptide: CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA , corresponding to N terminal amino acids 181-230 of Human SLC6A8

  • Positive control
    • MDA MB 435S cell lysate, human muscle tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab62196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 71, <36 kDa (predicted molecular weight: 71 kDa).Can be blocked with SLC6A8 peptide (ab216175). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

Target

  • FunctionRequired for the uptake of creatine in muscles and brain.
  • Tissue specificityPredominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
  • Involvement in diseaseCerebral creatine deficiency syndrome 1
  • Sequence similaritiesBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • SLC6A 8 antibody
    • SLC6A8 antibody
    • Creatine transporter 1 antibody
    • Creatine transporter SLC6A8 antibody
    • CRT antibody
    • CRTR antibody
    • CT 1 antibody
    • CT1 antibody
    • MGC87396 antibody
    • SC6A8_HUMAN antibody
    • Slc6a8 antibody
    • Sodium and chloride-dependent creatine transporter 1 antibody
    • Sodium- and chloride-dependent creatine transporter 1 antibody
    • Solute carrier family 6 (neurotransmitter transporter, creatine), member 8. antibody
    • Solute carrier family 6 member 8 antibody
    see all

Anti-SLC6A8 antibody images

  • Anti-SLC6A8 antibody (ab62196) at 2.5 µg/ml + MDA MB 435S cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG 1/ 50,000 - 1/100,000 dilution

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : <36 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human muscle tissue labelling SLC6A8 with ab62196 at 4-8µg/ml. Arrows indicate positively labelled skeletal muscle cells. Magnification: 400X.

References for Anti-SLC6A8 antibody (ab62196)

ab62196 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"