Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC7A10
  • Tested applications
    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: RSKPKCVHRL TESMTHWGQE LCFVVYPQDA PEEEENGPCP PSLLPATDKP SKPQ, corresponding to amino acids 470-523 of Human SLC7A10.

  • Positive control
    • Human pancreas tissue; RT 4, U 251 MG and Human liver lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse.
  • Tissue specificity
    Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
  • Sequence similarities
    Belongs to the amino acid-polyamine-organocation (APC) superfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAA1_HUMAN antibody
    • ASC-1 antibody
    • Asc-type amino acid transporter 1 antibody
    • D-serine transporter antibody
    • HASC 1 antibody
    • Slc7a10 antibody
    • solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 antibody
    • Solute carrier family 7 member 10 antibody
    • solute carrier family 7, (cationic amino acid transporter, y+ system) member 10 antibody
    • solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 antibody
    see all

Images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleoli. Recommended concentration of ab122751 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122751 at 1/200 dilution, staining SLC7A10 in Paraffin-embedded Human Pancreas tissue by Immunohistochemistry.
  • All lanes : Anti-SLC7A10 antibody (ab122751) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique

    Exposure time : 30 seconds

References

ab122751 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab122751.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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