Overview

  • Product nameAnti-SLC7A7 antibody
    See all SLC7A7 primary antibodies
  • Description
    Rabbit polyclonal to SLC7A7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 179-228 (WGTLVQDIFT YAKVLALIAV IVAGIVRLGQ GASTHFENSF EGSSFAVGDI) of Human SLC7A7 (NP_003973).

  • Positive control
    • PANC1 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab106610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionInvolved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes.
  • Tissue specificityHighest expression in kidney and peripheral blood leukocytes. Weaker expression is observed in lung, heart, placenta, spleen, testis and small intestine. Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, retinal pigment epithelial cells, and various carcinoma cell lines, with highest expression in a colon-carcinoma cell line.
  • Involvement in diseaseLysinuric protein intolerance
  • Sequence similaritiesBelongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
  • Cellular localizationBasolateral cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • LAT3 antibody
    • LPI antibody
    • Monocyte amino acid permease 2 antibody
    • MOP-2 antibody
    • MOP2 antibody
    • SLC7A 7 antibody
    • Slc7a7 antibody
    • Solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 antibody
    • Solute carrier family 7 member 7 antibody
    • y(+)L type amino acid transporter 1 antibody
    • y(+)L-type amino acid transporter 1 antibody
    • Y+L amino acid transporter 1 antibody
    • y+LAT-1 antibody
    • Y+LAT1 antibody
    • YLAT1_HUMAN antibody
    see all

Anti-SLC7A7 antibody images

  • Anti-SLC7A7 antibody (ab106610) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 56 kDa

References for Anti-SLC7A7 antibody (ab106610)

ab106610 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"