Overview

  • Product name
  • Description
    Rabbit polyclonal to SLC8A3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide: SAPEILLSLI EVCGHGFIAG DLGPSTIVGS AAFNMFIIIG ICVYVIPDGE , corresponding to a region within N terminal amino acids 144 - 193 of Human SLC8A3 (NP_150287)

  • Positive control
    • 721_B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab84708 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 103 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Relevance
    SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner.
  • Cellular localization
    Membrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • AW742262 antibody
    • MGC90626 antibody
    • Na+/Ca2+ exchange protein 3 antibody
    • Na+/Ca2+ exchanger 3 antibody
    • NAC3_HUMAN antibody
    • NCX3 antibody
    • SCL8A3 antibody
    • Sodium calcium exchanger form 3 antibody
    • Sodium/calcium exchanger 3 antibody
    • Sodium/calcium exchanger SLC8A3 antibody
    • Solute carrier family 8 sodium calcium exchanger member 3 antibody
    see all

Images

  • Anti-SLC8A3 antibody (ab84708) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 103 kDa
    Observed band size : 103 kDa
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

References

This product has been referenced in:
  • Heise N  et al. Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells. Am J Physiol Cell Physiol 300:C1306-13 (2011). WB . Read more (PubMed: 21307349) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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