Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 2
Solute carrier family 9 isoform 3 regulator 2
Solute carrier family 9 isoform A3 regulatory factor 2
SRY interacting protein 1
SRY-interacting protein 1
Tyrosine kinase activator protein 1
FunctionScaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.
Cellular localizationEndomembrane system. Nucleus. Apical cell membrane. Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern.