Overview

  • Product nameAnti-SLC9A9 antibody
    See all SLC9A9 primary antibodies
  • Description
    Rabbit polyclonal to SLC9A9
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide (Mouse). Immunogen sequence - QEQSPSPSSP TTKLALDQKS

Properties

Applications

Our Abpromise guarantee covers the use of ab56216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 72 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • FunctionMay act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintainance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell.
  • Tissue specificityUbiquitously expressed in all tissues tested. Expressed at highest levels in heart and skeletal muscle, followed by placenta, kidney, and liver. Expressed in the brain, in the medulla and spinal cord.
  • Involvement in diseaseNote=A chromosomal aberration involving SLC9A9 has been found in a family with early-onset behavioral/developmental disorder with features of attention deficit-hyperactivity disorder and intellectual disability. Inversion inv(3)(p14:q21). The inversion disrupts DOCK3 and SLC9A9.
    Defects in SLC9A9 are a cause of susceptibility to autism type 16 (AUTS16) [MIM:613410]. Autism is a complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate mental retardation. AUTS16 can be associated with epilepsy.
  • Sequence similaritiesBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • Cellular localizationLate endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5730527A11Rik antibody
    • 9930105B05 antibody
    • AI854429 antibody
    • FLJ35613 antibody
    • Na(+)/H(+) exchanger 9 antibody
    • Nbla00118 antibody
    • NHE 9 antibody
    • NHE-9 antibody
    • NHE9 antibody
    • Putative protein product of Nbla00118 antibody
    • SL9A9_HUMAN antibody
    • Slc9a9 antibody
    • Sodium/hydrogen exchanger 9 antibody
    • Sodium/proton exchanger NHE9 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger) isoform 9 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger) member 9 antibody
    • Solute carrier family 9 member 9 antibody
    see all

References for Anti-SLC9A9 antibody (ab56216)

ab56216 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab56216.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"