Overview

  • Product name
    Anti-SLFN14 antibody
  • Description
    Rabbit polyclonal to SLFN14
  • Specificity
    At least two isoforms of SLFN14 are known to exist; ab106406 will recognize both isoforms. ab106406 is predicted not to crossreact with other SLFN proteins.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A 16 amino acid synthetic peptide from near the C terminus of Human SLFN14 (NP_001123292).

  • Positive control
    • Mouse kidney tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 104 kDa.

Target

Images

  • Immunofluorescence of SLFN14 in mouse kidney tissue with ab106406 at 20 ug/mL.

  • Lane 1 : Anti-SLFN14 antibody (ab106406) at 1 µg/ml
    Lane 2 : Anti-SLFN14 antibody (ab106406) at 2 µg/ml

    Lane 1 : Mouse kidney tissue lysate
    Lane 2 : Mouse kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 104 kDa
    The lower band seen in the western blot may represent a post-translationally modified form of SLFN14.

References

This product has been referenced in:
  • Marconi C  et al. SLFN14-related thrombocytopenia: identification within a large series of patients with inherited thrombocytopenia. Thromb Haemost 115:1076-9 (2016). Read more (PubMed: 26769223) »
  • Fletcher SJ  et al. SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects. J Clin Invest 125:3600-5 (2015). Read more (PubMed: 26280575) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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