Overview

  • Product name
  • Description
    Rabbit polyclonal to Slit3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Cow
    Predicted to work with: Mouse, Rat, Chicken, Human
  • Immunogen

    Synthetic peptide:

    GKDSYVELASAKVR-C

    conjugated to KLH, corresponding to amino acids 1164-1177 of Human Slit3.

  • General notes
    Expiration date is 1 year from date of opening.

Properties

Applications

Our Abpromise guarantee covers the use of ab11018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Detects a band of approximately 145 kDa (predicted molecular weight: 169 kDa).

Target

  • Function
    May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
  • Tissue specificity
    Predominantly expressed in thyroid.
  • Sequence similarities
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 9 EGF-like domains.
    Contains 1 laminin G-like domain.
    Contains 20 LRR (leucine-rich) repeats.
    Contains 4 LRRCT domains.
    Contains 4 LRRNT domains.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ10764 antibody
    • KIAA0814 antibody
    • MEGF 5 antibody
    • MEGF5 antibody
    • Multiple EGF-like domains protein 5 antibody
    • Multiple epidermal growth factor like domains 5 antibody
    • Multiple epidermal growth factor-like domains protein 5 antibody
    • SLIL 2 antibody
    • SLIL2 antibody
    • SLIT 1 antibody
    • Slit 2 antibody
    • Slit 3 antibody
    • Slit homolog 3 (Drosophila) antibody
    • Slit homolog 3 antibody
    • Slit homolog 3 protein antibody
    • Slit-3 antibody
    • SLIT1 antibody
    • Slit2 antibody
    • Slit3 antibody
    • SLIT3_HUMAN antibody
    see all

Images

  • Anti-Slit3 antibody (ab11018) at 1/800 dilution + Bovine thyroid whole cell lysate at 35 µg

    Secondary
    Goat-anti-Rabbit IgG [H&L] at 1/10000 dilution

    Predicted band size : 169 kDa
    Observed band size : 145 kDa (why is the actual band size different from the predicted?)

References

This product has been referenced in:
  • Pi L  et al. CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J : (2012). WB . Read more (PubMed: 22611085) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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