Anti-Slit3 antibody (ab11018)
Key features and details
- Rabbit polyclonal to Slit3
- Suitable for: WB
- Reacts with: Cow
- Isotype: IgG
Overview
-
Product name
Anti-Slit3 antibody
See all Slit3 primary antibodies -
Description
Rabbit polyclonal to Slit3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Cow
Predicted to work with: Mouse, Rat, Chicken, Human -
Immunogen
Synthetic peptide:
GKDSYVELASAKVR-C
conjugated to KLH, corresponding to amino acids 1164-1177 of Human Slit3. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab11018 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/2000. Detects a band of approximately 145 kDa (predicted molecular weight: 169 kDa).
|
Notes |
---|
WB
1/500 - 1/2000. Detects a band of approximately 145 kDa (predicted molecular weight: 169 kDa). |
Target
-
Function
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors. -
Tissue specificity
Predominantly expressed in thyroid. -
Sequence similarities
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 9 EGF-like domains.
Contains 1 laminin G-like domain.
Contains 20 LRR (leucine-rich) repeats.
Contains 4 LRRCT domains.
Contains 4 LRRNT domains. -
Cellular localization
Secreted. - Information by UniProt
-
Database links
- Entrez Gene: 374173 Chicken
- Entrez Gene: 6586 Human
- Entrez Gene: 20564 Mouse
- Entrez Gene: 83467 Rat
- Omim: 603745 Human
- SwissProt: O75094 Human
- SwissProt: Q9WVB4 Mouse
- SwissProt: O88280 Rat
see all -
Alternative names
- FLJ10764 antibody
- KIAA0814 antibody
- MEGF 5 antibody
see all
Images
-
Anti-Slit3 antibody (ab11018) at 1/800 dilution + Bovine thyroid whole cell lysate at 35 µg
Secondary
Goat-anti-Rabbit IgG [H&L] at 1/10000 dilution
Predicted band size: 169 kDa
Observed band size: 145 kDa why is the actual band size different from the predicted?
Datasheets and documents
-
SDS download
-
Datasheet download
References (2)
ab11018 has been referenced in 2 publications.
- Kong Y et al. Slit-miR-218-Robo axis regulates retinal neovascularization. Int J Mol Med 37:1139-45 (2016). PubMed: 26935869
- Pi L et al. CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J : (2012). WB . PubMed: 22611085